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Research & Development  

LYOFAL has a Research & Development Department which works out freeze-drying parameters.

  • Determining of critical temperatures
  • Feasibility study of lyophilisation
  • Formulation study (cryoprotector and lyoprotector)
  • Freezing path optimisation study
  • Optimisation study of a lyophilisation cycle

This department uses equipments to make eutectic measures in order to optimize the freeze-drying cycles, to draw up regulatory support and to better make the equipment profitable. It offers assistance to the customer within the framework of his development project.

  • Conseil et assistance aux techniques de lyophilisation

Equiped with :

  • Freeze drying microscope to determine critical temperature (eutectique)
  • Coulometer to measure the residual humidity left using the Karl Fisher method
  • Tests using pilot scale freeze dryer (protocol may be adapted to industrial scale freeze dryer)


    A freeze drying microscope.





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